When a pathogenic bacterium approaches, the phage can recognize membrane specific proteins. This allows it to anchor itself and generate the infection.
A
Contact
Address
Vicuña Mackenna 4860, Macul,
Región Metropolitana. Santiago,
Chile (8320000).
Lab
A Space to
Research,
Innovate &
Develop
We have a dynamic and collaborative laboratory, thanks to its infrastructure and state-of-the-art equipment.
What we do
Increase
welfare
and
results
In PhageLab we develop customized projects, according to the problem that each client needs to solve. We currently work with large production companies in the Poultry, Swine, Livestock and Aquaculture industries, both in Chile and around the world.
Our technology works
1
Identification and isolation of bacteria of interest
We intervene in the industrial process to identify and characterize bacteria of interest, using microbiology tools, genomics and bioinformatics.
2
Search and characterization of bacteriophages.
We search for, isolate, characterize and sequence the appropriate bacteriophages to eliminate the bacteria of interest.
3
Bioprocesses and industrial manufacturing
We implement bacteriophage production processes in cGMP quality and adapt the product according to the customer’s needs and in compliance with the corresponding sanitary regulations.
Intestinal lumen
Our
Digestive
Sys
tem
The adherence complex IG-GLICAN allows our phages to accompany the intestinal transit, preventing pathogenic bacteria from colonizing the environment. Here’s how they do it.
B
The phage enters its genetic material and uses all its replicative machinery. It introduces itself to the bacteria and multiplies, creating various copies.
C
Once replicated, the phages secrete enzymes which destabilize the bacterial membrane causing its lysis, releasing multiple copies of phages ready to infect other pathogens and repeat the process.
